Cadence, NVIDIA Extend Partnership for Accelerated Computing and Agentic AI

Cadence Design Systems, a leading computational software company, has announced that it is expanding its multi-year collaboration with NVIDIA, focusing on accelerated computing and agentic AI. 

This partnership addresses global technology challenges by driving innovation across various industries and involves Cadence leveraging NVIDIA’s latest Blackwell architecture to accelerate its engineering and scientific solutions. 

This includes reducing computational fluid dynamics simulation times by up to 80 times, from days to minutes, and accelerating the Cadence Spectre X Simulator by up to 10 times.

Jensen Huang, NVIDIA CEO, noted, “Accelerated computing and agentic AI are setting new standards for innovation across industries.” 

Using its Fidelity CFD Platform, Cadence also successfully ran multi-billion cell simulations on NVIDIA GB200 GPUs in under 24 hours. It would have previously required a top 500 CPU cluster with 100,000 cores and several days to complete. 

The company expressed that it will continue to leverage Blackwell for simulation and help the aerospace industry reduce the amount of wind tunnel tests by reducing cost and expediting time to market.

New Era for Accelerated Computing

Additionally, the partnership involves the companies working together on a full-stack agentic AI solution for electronic and system design, as well as science applications. This will integrate Cadence’s JedAI Platform with NVIDIA’s NeMo generative AI framework and the Llama Nemotron Reasoning Model. 

Anirudh Devgan, president and CEO at Cadence, says, “We’re enabling the delivery of today’s infrastructure AI and agentic AI and transforming the principled simulations that underpin physical AI and sciences AI.”

The collaboration is expected to transform industries by enabling complex simulations that were previously impossible, driving efficiency, and fueling scientific discovery. It will also deliver breakthroughs in simulation, optimisation, and design. 

In his keynote address at the NVIDIA 2025 GTC summit, he mentioned that until now, the giant had been using general-purpose computers running software super slowly to design accelerated computers for everybody else. 

But with the entry of optimised CUDA software, “now our entire industry is going to get supercharged as we move to accelerated computing.”

Cadence Molecular Sciences (OpenEye) is also integrating NVIDIA BioNeMo NIM microservices with its cloud-native molecular design platform, Orion. Cadence has also been one of the first adopters of NVIDIA Omniverse Blueprint for AI factory digital twins. 

Cadence and NVIDIA are leading the way in creating an ecosystem of high-quality models, allowing equipment manufacturers and data centre companies to quickly create digital twins.